Intra uterine insemination (IUI)
Intra uterine insemination involves preparing sperm in the lab, then putting the best sperm directly into the uterus in a procedure that’s a bit like having a cervical smear.
IUI is the next step up from Clomiphene and Letrozole, and it can be used for quite a wide range of causes of infertility.
In nature, only one in a hundred sperm that are ejaculated reach the uterus, so IUI works by giving sperm a head-start in their journey to the egg. IUI is usually combined with a medication like Clomiphene to increase the number of eggs ovulated from one to two or three.
IUI cycles typically involve:
- some blood tests
- 1-2 ultrasound scans
- injections, which people usually give themselves at home.
IUI is usually offered as a course of up to four cycles. One review consult with the doctor after four cycles of treatment is included.
Around 40–50% of women aged 37 and younger have a child within four cycles, and the main side effect is a 10-15% chance of twins.