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Frequently asked questions

Can I opt for an alternative to HSA?

At present, HSA is a crucial component in IVF media for successful embryo development. Although recombinant alternatives were considered, they are not widely used due to insufficient data on efficacy compared to natural HSA.

In a validations study conducted at Fertility Associates in 2016, HSA outperformed SSS (synthetic serum replacement) in terms of embryo utilisation rate (2/3rds of cases had more blastocysts with HSA vs SSS).

Some IVF media incorporate other protein sources, including α and β globulins. However, these alternatives may increase ammonium levels, potentially affecting blastocyst quality, gene expression, and pregnancy outcomes.

Is it possible to use HSA from my own blood?

Unfortunately, this is not feasible due to complex regulatory and technical constraints.

Can the HSA in my IVF media guarantee it is free from mRNA?

While absolute guarantees are not feasible in biological systems, stringent testing standards minimise any risk of residual mRNA. The HSA used is derived from thoroughly screened blood donations and follows rigorous purification processes.

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The Biological Clock

This tool indicates:

  • Natural conception per month if you have no fertility issues
  • IVF success rate at the same age
  • When to seek help after months of unsuccessful attempts

If you are concerned at any stage – we recommend booking a doctor appointment or a free nurse consultation. The sooner you make a plan the better your chances in the long term.

When to seek advice early
  • If you have polycystic ovaries, endometriosis, or have been through a cancer diagnosis; we recommend you get in touch quickly so we can talk you through all your options and give you the greatest possible chance of success.
  • If you’re a single woman considering motherhood in the future; it’s best to approach us early and consider egg freezing as this can be an option for you while you have a higher ovarian reserve and healthier eggs.
Set your age and the months you’ve been trying to conceive
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Your chance of having a baby per month for fertile couples
Your chance of having a baby per IVF cycle (if experiencing infertility)

Body Mass Index calculator

Being overweight or underweight can reduce fertility, so it is important to keep your body weight within the normal healthy range.

Body Mass Index (BMI) is an indication of your body weight and can be calculated by dividing weight by height. You should aim for a BMI of between 20 and 25, as this will optimise your chances of conception.

Woman’s BMI below 19

Even in these modern times, nature knows best. If a woman's BMI falls below 19, the body senses famine and ovulation is switched off to prevent the risk of having a baby with malnutrition. Excessive exercise can reduce body fat and increase muscle mass to a point where periods cease for the same reason. Risk of miscarriage is also increased in women with a low BMI.

Being underweight

If a woman's BMI falls below 19, the body senses famine and ovulation is switched off to prevent the risk of having a baby with malnutrition. Excessive exercise can reduce body fat and increase muscle mass to a point where periods cease for the same reason. Risk of miscarriage is also increased in women with a low BMI.

BMI’s greater than 30

This can reduce fertility by 50%. Pregnancy for women with a 30+ BMI is often associated with problems such as maternal diabetes, high blood pressure, big babies and increased risk of caesarean section.

Add your height and weight to calculate your BMI
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